Three useful clamps for cardiovascular surgery

Useful adjuncts for vitreoretinal surgery.

Many vitreoretinal procedures are performed in offices and hospitals where cost control is important. We describe three useful devices and techniques that facilitate these procedures at minimal expense and often greater convenience. These include an accurate method for localising the pars plana without the use of callipers, an inexpensive, reliable, pressure regulated air pump for fluid-air exc...

Narcotic anesthesia for cardiovascular surgery.

RNA Polymerase Clamps Down

RPB1 (which is not present in bacterial RNAP) is not Gene expression in all cells requires synthesis of mRNAs resolved in the structures. by an evolutionarily conserved, multisubunit RNA polyAs RNAP transcribes (Figure 1B), DNA enters the enmerase (RNAP). A series of recent breakthroughs in zyme in the first chamber, termed the jaw-lobe module. X-ray crystallography of RNAP has begun to reveal ...

Molecular chaperones: Clamps for the Clps?

The Clp/Hsp100 molecular chaperones are unusual in their ability to tease apart protein aggregates and complexes. Recent results make a good case that these chaperones bind substrates via PDZ-like domains; this may reflect a general strategy for manipulating the] assembly state of substrate proteins.

Is estimating lifetime cardiovascular risk useful?